The Aetiology of ‘Aerotoxic Syndrome’- A Toxico-Pathological Viewpoint There is an enormous literature on the acute toxicity of organo-phosphate pesticides and nerve gas agents through acetyl-cholines ...(..) ..On the one hand there are a number of aircrew who have been acutely impaired in flight incidents, with others becoming chronically ill, many of whom have had to retire as a result. This is acknowledged by many aircrew organizations and some doctors and scientists ...(..)... organo-phosphate pesticides and nerve gas agents through acetyl-cholinesterase inhibition, which will already be familiar to the readership. This aspect was reviewed by the UK Committee on Toxicity in the context of cabin air quality . Read
C V Howard1*, S Michaelis2 and A Watterson2 1Centre for Molecular Biosciences, University of Ulster, UK 2Occupational and Environmental Health Research Group, University of Stirling, UK
Smoke/fumes in the cockpit. Rayman RB, McNaughton GB.
During the period 1970-80, there were reported in USAF 89 incidents of smoke/fumes in the cockpit during flight. The origin of the fumes in most cases was organic petroleum derivatives, which caused a multitude of symptoms including CNS dysfunction and mucous membrane irritation. Flight surgeons should be well-read in aerospace toxicology because of the threat to flying safety posed by the many fluids and substances necessary for the operation of today's modern aircraft. Read
Principles and Practice - Aviation Medicine
For aviation the only logical method of dealing with this problem is to eliminate carbon monoxide from the cabins and cockpits of aircraft. The onset of carbon monoxide poisoning is so insidious and its effects so disastrous to anyone piloting an airplane that preventativc measures arc the only ones to be relied on. (by George Armstrong (February 17, 1899 – February 5, 1983) was a Major General in the U.S. Air Force, a physician, and an airman. He is widely recognized as a pioneer in the field of aviation medicine.) Read
Orientations sur les pratiques éducatives, de formation et de compte rendu concernant les émanations
Orientations sur les pratiques éducatives, de formation et de compte rendu concernant les émanations (Numéro de commande : CIR 344 ISBN 978-92-9249-873-3 ). -OACI Read
A comparison of fresh and used aircraft oil for the identification of toxic substances linked to aerotoxic syndrome David Megson et al .Read
Adverse health effects following exposure to jet oil mist during commercial flights. - J.C.Balouet Read
Journal of biological physics and chemistry – the problem of contaminated aircraft cabin air.
Published jointly by Collegium Basilea (Institute of Advanced Study) and Association of Modern Scientific Investigation on 12th december, volume 14 number 4. - Erratum Jeremy J. Ramsden Read
Summary of documents that address potential flight safety impact of exposure to confirmed/suspected oil-contaminated ventilation air on commercial and military aircraft, and supporting documentation - J.Andersen Read
Ill health following reported exposure to contaminated air on commercial aircraft: psychosomatic disorder or neurological injury? Dr Sarah MacKenzie Ross Read
Jet engine oil consumption as a surrogate for measuring chemical contamination in aircraft cabin air - Jeremy J. Ramsden Read
Autoantibodies to nervous system-specific proteins are elevated in sera of flight crew members: biomarkers for nervous system injury. Abou-Donia MB1, Abou-Donia MM, ElMasry EM, Monro JA, Mulder MF. Read
Autoantibody markers of neural degeneration are associated with post-mortem histopathological alterations of a neurologically injured pilot Read
M.B. Abou-Donia,1, * F.R.W. van de Goot2 and M .F.A. Mulder
Grundlagen, Pathophysiologie und Therapie mit der therapeutischen Apherese - Drs: Richard Straube, Klaus Bolst, Hans-Peter Donate Read
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